WebPaclitaxel is a promising esophageal cancer chemotherapy drug, with an efficacy of approximately 32% as monotherapy in patients with locally advanced and metastatic esophageal cancer. 13 Paclitaxel inhibits tubulin dissociation, thereby inhibiting mitosis, which blocks cell proliferation during the G2/M phase of the cell cycle and promotes the ... WebFind technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes links to find …
Cisplatin Uses, Side Effects & Warnings - Drugs.com
WebEpithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related death. The high mortality and morbidity associated with EOC are mostly due to late diagnosis and chemotherapy drug resistance. Currently, the standard first-line chemotherapy regimen is systemic administration of platinum-based chemotherapy combined with a taxane. A … WebNov 12, 2024 · Premedicate with antiemetics.Myelosuppression: cisplatin injection can cause severe myelosuppression with fatalities due to infections. Monitor blood counts … moderate squamous dysplasia cin ii
CISplatin Injection - Food and Drug Administration
WebSep 3, 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a phase II protocol, using fluorouracil 350 mg/m2/d by continuous intravenous (IV) infusion over 5 days, followed on the sixth day by a 2-hour IV infusion of cisplatin 50 mg/m2, administered during the … WebFeb 26, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin changes where the injection was given; bone ... WebNiraparib (Zejula) may be used in some situations to treat ovarian cancer. In women with or without a BRCA gene mutation: Niraparib might be used as maintenance treatment for advanced ovarian cancer, where the cancer has shrunk with first-line chemotherapy containing cisplatin or carboplatin. In women with a BRCA gene mutation: moderate signs of dehydration