Cisplatin c57
WebChemotherapeutic doses of cisplatin impair spermatogenesis and ultimately cause azoospermia and infertility in some men. The mechanism by which cisplatin damages testicular germ cells is poorly understood. Cisplatin's impact is first detected hours after exposure in the formation of DNA cross-links followed by weeks of testicular damage. … WebCisplatin is also sometimes used to treat head and neck cancer (including cancer of the mouth, lip, cheek, tongue, palate, throat, tonsils, and sinuses), lung cancer, cancer of the …
Cisplatin c57
Did you know?
WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … WebAfter treating cisplatin-induced AKI mice with meclofenamic acid, an FTO inhibitor, m 6 A expression increases and kidney injury is exacerbated through p53-mediated apoptosis pathways. 65 Shen et ...
WebOct 1, 2013 · Cisplatin-induced AKI in mice Eight-week old C57BL/6 male mice, purchased from the Jackson Laboratories, were housed for one week before experiments in the animal facility of the Charlie Norwood VA Medical Center at Augusta. These mice had free access to water and regular chow. Web江西中洪博元生物技术有限公司是以研发人类疾病动物模型(动物造模，疾病动物造模)为核心业务的国家级高新技术企业。公司已经成功开发300种人类疾病动物模型，用于为cro药效筛选、药物代谢、非glp安全性评价、生命科学实验、医学科技成果转化提供研究对象和平台
WebApr 13, 2024 · Spankovich et al. showed a reduced cisplatin-related hearing loss by cold water irrigation in guinea pigs (Spankovich et al., 2016). In an alternative rodent experiment, the otoprotective effect of hypothermia applied through a custom-made cooling device was evaluated in a cochlea implantation situation. ... C57-Black-6/J (C57Bl6/J) mice ...
WebJan 2, 2005 · Normal adult C57/Bl/6J mice were exposed to 1, 2, or 4 rounds of 1, 2.5, or 5 mg/kg cisplatin in a regimen designed to resemble clinical chemotherapeutic exposure (1 injection daily for 5 days ...
WebNov 1, 2024 · Cisplatin rapidly increases PD-L1 mRNA and protein levels in lung cancer cell lines. In tumor bearing mice injection of cisplatin significantly enhances PD-L1 … cougar okotoksWebFeb 23, 2024 · The combination of pemetrexed and cisplatin remains the reference first-line systemic therapy for malignant pleural mesothelioma (MPM). Its activity is moderate because of tumor aggressiveness, immune-suppressive environment and resistance to chemotherapy-induced immunogenic cell death (ICD). cougar snake venom reviewsWebFeb 1, 2024 · Based on the constructed C57 mice with VDR knockout and VDR overexpression, we established a cisplatin-induced acute kidney injury model. 72 h after intraperitoneal injection with cisplatin, kidney injury indicators including creatinine, urea nitrogen, cystatin C, the kidney-body weight ratio and tubular injury score in KO + CP … cougar snake venomhttp://www.zhbybio.com/newsinfoen/7783.html?page=70 cougar zapatosWebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), … cougar zivotinjaWebJun 5, 2014 · Adult C57 mice received one cycle of 2.5, one cycle of 5.0, or two cycles of 2.5 mg/kg/day cisplatin in PBS. The cumulative dose administered to each group and the … cougar snake venom face maskWebOct 7, 2024 · C57BL/6 mice are one of the most commonly used mouse strains in research, especially in kidney injury studies. However, C57BL/6 mice are resistant to chronic … cougar snake venom day moisturizer