Cyp1a2 remmers
WebHHMI’s Janelia Research Campus in Ashburn, Virginia, cracks open scientific fields by breaking through technical and intellectual barriers. Our integrated teams of lab scientists … WebVertalingen in context van "CYP1A2-remmers waarschijnlijk" in Nederlands-Frans van Reverso Context: CYP1A2-remmers: Omdat CYP1A2 bij het metabolisme van duloxetine is betrokken, zal gelijktijdig gebruik van duloxetine en sterke CYP1A2-remmers waarschijnlijk resulteren in hogere concentraties duloxetine.
Cyp1a2 remmers
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WebDec 27, 2024 · The CYP1A2 gene is located on chromosome 15 and spans about 7.8 kilobases. There are more than 30 alleles identified to date, in particular in the 5′ flanking … WebCYP1A2 Species Human Location Chr.15: 74748759 -74749267 on GRCh38 Amp. Len. 509 Transcripts 1 RefSeq (NM) Availability Made to Order Catalog # A15629, A15630 Non …
WebCYP1A2 is involved in the metabolism of, e.g., agomelatin, caffeine, clozapine, duloxetine, propranolol, tizanidine, and zolmitriptan, as well as some endogenous compounds, such … WebCYP1A2 is an inducible member of the cytochrome P450 (CYP) drug metabolizing gene family, important for metabolism of caffeine and antipsychotics. Annotation Background …
WebHuman cytochrome P450 enzyme 1A2 (CYP1A2) is one of the most important cytochrome P450 (CYP) enzymes in the liver, accounting for 13% to 15% of hepatic CYP enzymes. … CYP1A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1A2 localizes to the endoplasmic reticulum and its expression … See more Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the human body. In humans, the CYP1A2 enzyme is encoded … See more Expression of CYP1A2 appears to be induced by various dietary constituents. Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2. Lower … See more • Cytochrome P450 oxidase See more • Human CYP1A2 genome location and CYP1A2 gene details page in the UCSC Genome Browser. • Overview of all the structural information available in the PDB for See more Following is a table of selected substrates, inducers and inhibitors of CYP1A2. Inhibitors of CYP1A2 can be classified by their potency, such as: • Strong … See more • Meijerman I, Beijnen JH, Schellens JH (2006). "Herb-drug interactions in oncology: focus on mechanisms of induction". The Oncologist. 11 (7): 742–52. doi:10.1634/theoncologist.11-7-742. PMID 16880233. • Smith G, Stubbins MJ, Harries LW, Wolf CR (Dec … See more
WebMar 21, 2024 · GeneCards Summary for CYP1A2 Gene CYP1A2 (Cytochrome P450 Family 1 Subfamily A Member 2) is a Protein Coding gene. Diseases associated with CYP1A2 include Porphyria Cutanea Tarda and Acetaminophen Metabolism . Among its related pathways are Imipramine/Desipramine Pathway, Pharmacokinetics and Metapathway …
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