Eif2s2 reprogramming
WebeIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and … WebFeb 6, 2024 · EIF2S2 is highly expressed in tumors and is associated with malignant features as well as patient prognosis. Functional assays …
Eif2s2 reprogramming
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WebEIF2S2 Promotes Tumor Growth and Progression in GI Cancers To further analyze the effects of EIF2S2 on GI cancers, we knocked down or overexpressed EIF2S2 in CRC, GC, and HCC cell lines (Fig-ures S3A–S3C) and then performed colony and cell proliferation as-says. We found that EIF2S2 is highly expressed in HCT-116 cells and WebBackground: Hepatocellular carcinoma (HCC) is a malignant tumor with a high fatality rate, predicting poor prognosis and therapeutic effect. Screening potential prognostic genes in HCC could be a creative way to advance clinical treatment. Eukaryotic translation initiation factor 2 subunit beta (EIF2S2) has reportedly been linked to several tumors, including …
WebWestern blot analysis of extracts of various cell lines, using EIF2S2 antibody (STJ116709) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s. WebEIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of …
WebApr 8, 2024 · Finally, we explored the effects of EIF2S2 on prognosis in GI cancer patients and revealed that high expression of EIF2S2 is associated with poor survival of CRC (Figure 1 G, p = 0.023) and HCC patients (Figure S2 D, p = 9.1E−6 and 0.012). Taken together, these results suggested that EIF2S2 plays oncogenic roles in GI cancers. Web2 Abstract The agouti-yellow (Ay) deletion is the only genetic modifier known to suppress testicular germ cell tumor (TGCT) susceptibility in mice or humans. The Ay mutation deletes Raly and Eif2s2, and induces the ectopic expression of agouti, all of which are potential TGCT-modifying mutations. Here we report that the reduced TGCT incidence of …
WebPharos : Target Details - EIF2S2 Targets Ligands About Tutorials lightbulb feedback Protein Classes help help No PANTHER Classes or DTO Classes found Expression Data (0 …
WebMar 21, 2024 · Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding … soy insoportableWebAug 11, 2015 · Translation of messenger RNA (mRNA) into proteins is key to eukaryotic gene expression and begins when initiation factor-2 (eIF2) delivers methionyl initiator … team pick me up quotesWebEukaryotic translation initiation factor 2 subunit beta (EIF2S2) has reportedly been linked to several tumors, including liver cancer, but the prognostic predictions remain unknown. … soyinka metaphysical poetryWebThe bit clock rate is determined by the sample rate and i2s_config_t configuration parameters (number of channels, bits_per_sample). bit_clock = rate * (number of … soy ink sealhttp://ko.cwru.edu/publications/heaney.pdf soy interaction with thyroid medicationWebOct 5, 2024 · Results: EIF2S2 is highly expressed in HCC patients and is associated with poor prognosis. The expression of EIF2S2 was also correlated with age, clinical stage … soy insensible a tiWeb10227-1-AP targets EIF2S2 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. soy in mexico