WebBenecel™ hypromellose (hydroxypropyl-methylcellulose or HPMC) is a versatile excipient with a variety of applications. HPMC is the most widely used polymer in hydrophilic matrix systems with widespread use in controlled-release dosage forms. The Benecel™ family of pharmaceutical products, including Benecel™ XR and XRF HPMC, custom grades ... WebDec 1, 2016 · The optimum conditions were found to be 0.92% of HPMC and 15% of PN F127. Under these conditions, the predicted CPR, BF and viscosity were found to be …
Interaction between mucoadhesive cellulose derivatives and …
WebJul 8, 2002 · At the used concentration, some of the examined isotonicity agents had effect on the viscosity of TM gel. However, the viscosity of gel increased as the PF127 concentrations increased. The viscosity of formulations containing thickening agents was in the order of PF–MC 3%>PF–HPMC 2%>PF–CMC 2.5%>PF127 15%. WebF127 and 3% (w/w) HPMC or 1% (w/w) NaCMC are promising as topical drug delivery systems, mainly on mucosal surfaces. They were biocompatible when tested against Artemia salina, and also able to release a model of hydrophilic drug in a controlled manner. Keywords: hydrogel; polymer blends; sodium carboxymethylcellulose; hydroxypropyl ... ddr4 配線ルール
In vitro and in vivo evaluation of Pluronic F127-based ocular delivery ...
WebJun 12, 2000 · The overall objective of this study was to develop pluronic F127 (PF127)‐containing formulations of pilocarpine hydrochloride (PHCL) suitable for … WebAug 1, 2002 · The viscosity of formulations containing thickening agents was in the order of PF-MC 3%>PF-HPMC 2%>PF-CMC 2.5%>PF127 15%. ... was observed when varying concentrations of Pluronic® F127 and CMC ... WebJul 8, 2002 · Pluronic F127 (PF127) consists of polyoxyethylene units (70%) and polyoxypropylene blocks (30%) (Lin and Sung, 2000). ... MC, HPMC and CMC Na are of high molecular weight, dissolve in water and yield much more viscous solutions compared with 15% PF127 gel without additives. The viscosity of gels was in the order of PF–MC … ddr4 メモリ 付け方