Lamp2 lamp1
TīmeklisLamp-2:溶酶体膜蛋白,可用于监测自噬体与溶酶体融合。 LysoTrackerTM 探针:有红或蓝色可选,显示所有酸性液泡。 pDsRed2-mito:载体,转染后表达一个融合蛋白(红色荧光蛋白+线粒体基质定位信号),可用来检测线粒体被自噬掉的程度(Mitophagy)。 MitoTraker探针:特异性显示活的线粒体,荧光在经过固定后还能保留。 Hsp60:定 … TīmeklisMoreover, in Azacytidine (Aza)-treated MDS cell lines and cells from MDS/AML patients, a progressive reduction in LAMP2 expression was correlated with a loss of sensitivity to Aza. 11 Bao et al found that the downregulation of LAMP2 in the lung cancer cells increased their resistance to Temozolomide. 26 In LAMP1/LAMP2 double-knockout …
Lamp2 lamp1
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Tīmeklis2024. gada 18. jūl. · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite … TīmeklisThe area under the curve (AUC) of LAMP1 was significantly higher than that of LAMP2 (Figure 3, AUC LAMP1 =0.593, AUC LAMP2 =0.534, P<0.05), which indicated that LAMP1 is a more sensitive marker than LAMP2 in the prognosis of ESCC.
TīmeklisA. The quantification of the colocalization between a lysosomal protein such as LAMP2 and LC3 could be used via a standard immunofluorescence protocol (fixation using … TīmeklisLysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and are heavily glycosylated at the amino …
TīmeklisPlasmid LAMP1-GFP from Dr. Ron Vale's lab contains the insert LAMP1/RE72002 and is published in J Cell Sci. 2006 Feb 15. 119(Pt 4):659-70. This plasmid is available through Addgene. Image: Illustrated plasmid map in PNG format. GenBank File: Plasmid sequence and annotations. Use text editor or plasmid mapping software to view … TīmeklisThe normalized integrated density ratio of LAMP1/LAMP2 ( Fig. 1 E) or cathepsin D/LAMP1 ( Fig. 1 J) was robustly reduced in LAMP1- or cathepsin D–depleted neurons, respectively. Western blotting consistently showed a selective depletion of LAMP1 or cathepsin D by their corresponding siRNAs ( Fig. 1 K ).
Tīmeklis2024. gada 30. janv. · In addition, recent work by our group observed that Lamp1, but not Lamp2, is significantly upregulated (Log 2 Fold, 1.08; Padj 4.66E-15), in activated microglia from Npc1-/-mice . This is in contrast to microarray data showing reduced expression of Lamp1 in the whole cerebellum of Npc1-/-mice [40, 41]. These results …
Tīmeklis2024. gada 30. marts · TMT impairs lysosomal function in Neuro-2a cells. (A) and (B) Representative immunoblots and quantification analysis of LAMP1 and LAMP2 in Neuro-2a cells treated with TMT at different concentrations (0, 2, 4, or 8 μM) for 24 h. ACTB was used as the internal standard for protein loading. (C) DQ-BSA staining … trader joe\u0027s top items 2023Tīmeklis2016. gada 21. okt. · LAMP-1 and LAMP-2 have distinct functions, and the presence of both proteins together is required for the essential regulation of autophagy to avoid … trader joe\u0027s top frozen mealsTīmeklis2024. gada 14. maijs · Immunoblotting revealed a dose-dependent increase of LAMP2 (Fig. 3a) and LAMP1 (Fig. 3b) in cytosolic fractions, while no significant alteration was observed in the remaining lysosomal... the rustic event center hopkinsville kyTīmeklisLysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular localization of lysosomal … the rustic fillyTīmeklisLAMP2. LAMP2 mutations produce the multisystemic disorder, Danon disease, in which neurologic, skeletal muscle, and hepatic involvement occur with cardiomyopathy. … the rustic farmhouse sumner waTīmeklisAnti-LAMP2 Antikörper [H4B4] (A86605) 15 Bewertungen 85 Produktreferenzen. 100µg / £160. Beschreibung: Mouse monoclonal [H4B4] antibody to LAMP2. ... Mouse monoclonal (5H6) antibody to LAMP1. Anwendungen: WB, ICC/IF, IHC: Reaktivität: Human: Konjugat: Unconjugated: Produkt anzeigen 10µl Versuchsgrößen. Anti … the rustic flag company stole from meTīmeklisA low luminal pH requires an intact lysosomal membrane barrier composed of ubiquitous highly glycosylated, lysosome-associated membrane proteins including LAMP1 and LAMP2 . LAMP2 also regulates the intracellular transport of hydrolases to lysosomes after sorting from the trans-Golgi network, and lysosomal membrane fusion with … the rustic flag company usa today