Lamp2 lamp2a
TīmeklisIsoform LAMP-2C Modulates chaperone-mediated autophagy. Decreases presentation of endogenous antigens by MHCII. Does not play a role in the presentation of … Tīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left …
Lamp2 lamp2a
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TīmeklisLAMP1 (lysosomal-associated membrane protein 1) and LAMP2 are the most abundant protein components of lysosome membranes. Both LAMPs have common structures consisting of a large lumenal domain composed of two domains (N-domain and C-domain, which are membrane-distal and -proximal, respectively), both with the β … Tīmeklis2024. gada 24. nov. · Lysosomal p38 MAPK directly phosphorylates the CMA receptor LAMP2A at T211 and T213, which causes its membrane accumulation and active conformational change, activating CMA. ... myc-wt-LAMP2, mt ...
Tīmeklis购买LAMP2A兔多克隆抗体(ab18528)，LAMP2A抗体经WB验证，可与人,小鼠样本反应。131篇文献引用，15个独立用户反馈。 ... ab18528 staining LAMP2 in MCF7 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% PBS-Tween for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M ... TīmeklisCritically, Lamp2a is required for HCC xenograft growth in vivo by helping cells to avoid apoptosis and promoting cell proliferation. Furthermore, a significant correlation …
TīmeklisLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Tīmeklis2024. gada 8. febr. · LAMP2A decrease enhances the lysosomal damage induced by lysosomotropic agents, ultimately leading to cell death. The effect is cancer-specific, as JNK inhibition does not decrease LAMP2A in...
Tīmeklis2024. gada 28. marts · 在这项研究中，研究人员发现含有与KFERQ基序相关的氨基酸序列的蛋白质被包装到外泌体的亚群中。 研究人员确定以下几种蛋白是该机制的基本组成部分：溶酶体相关膜蛋白2的同工型A (LAMP2A)，此前被认为是一种将含有KFERQ的底物靶向溶酶体的蛋白质；以及分子伴侣热休克蛋白HSC70。 此外，研究人员证明蛋白 …
TīmeklisLysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and are heavily glycosylated at the amino … can i get extended warranty if car bad engineTīmeklisSee all LAMP2A primary antibodies Description Rabbit monoclonal [EPR4207 (2)] to LAMP2A - Lysosome Marker Host species Rabbit Tested applications Suitable for: … fittings wholesalerTīmeklisSynthetic peptide corresponding to Human LAMP2A aa 350 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. LAMP2 has 3 distinct isoforms, … fitting take offTīmeklisThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the … fitting sweatpants in drawerTīmeklis2024. gada 25. marts · LAMP2A originates from the alternative splicing of the LAMP2 gene, which contains nine exons, including three different splice variants of the exon 9 (A, B, and C) ( Fig. 1A ). All splice … fittings with disposable bottle male endTīmeklis2024. gada 12. nov. · Abstract. Lysosome-associated membrane protein type 2A (LAMP2A) is a key protein in the chaperone-mediated autophagy (CMA) pathway. … fitting swivel batherTīmeklis2024. gada 25. marts · Here, we describe a mechanism whereby proteins containing a KFERQ motif pentapeptide are loaded into a subpopulation of exosomes in a … can i get evicted without a lease