Webbför 2 dagar sedan · In this study, we assume that deep learning model learns the nonlinear interaction between molecular environment (expression profile of ferroptosis regulators) and ferroptosis regulation score (potential regulation level of ferroptosis), so as to make accurate prediction. Webb22 dec. 2024 · Phosphorylase kinase G2 (PHKG2) can regulate iron availability of lipoxygenase, including arachidonate LOX12 (ALOX12), ALOX12B, ALOX15, and …
Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis
Webb21 mars 2024 · Ferroptosis is a newly discovered form of regulatory cell death induced by iron-dependent lipid peroxidation. Infection with Helicobacter pylori (H. p… Webb29 mars 2024 · PHKG2, IREB2, and CISD1 play an important role in ferroptosis by their function in iron metabolism balance. The phosphorylation of HSP27 induces ferroptosis resistance through blocking cytoskeleton-mediated iron absorption. EGLN1 can upregulate LSH expression by limiting HIF 1α. chinese american hydrologist sherry chen
PHKG2 regulates RSL3-induced ferroptosis in Helicobacter pylori …
Webb20 mars 2024 · In conclusion, PHKG2 facilitates RSL3-induced ferroptosis in H. pylori-positive GC cells by promoting ALOX5 expression. These findings may contribute to a better understanding of the unique pathogenesis of H. pylori-induced GC and allow for maximum efficacy of genetic, cellular, and immune therapies for controlling ferroptosis … Webb7 juni 2024 · Background: Ferroptosis, a regulated cell death which is driven by the iron-dependent peroxidation of lipids, plays an important role in cancer. However, studies about ferroptosis-related Long non-coding RNAs (lncRNAs) in breast cancer (BC) are limited. Besides, the prognostic role of ferroptosis-related lncRNAs and their relationship to … WebbAlthough some publications investigated the correlations between ferroptosis and LUAD, [10] [11][12][13] this study aimed to explore multi-omics data on LUAD including mRNA expression, protein ... chinese american historical figures