Rat's 27
TīmeklisThe AY-27 rat bladder tumor cell line is a urothelium-derived transitional cell carcinoma (3) and is the most widely used animal model for bladder cancer. AY-27 cells are tumorigenic and are characterized by low adenylate cyclase activity (4), lack of FasL expression, and positive staining for the urothelial marker cytokeratin-7.5 Tumors ... TīmeklisCD27 is also known as S152 and T14. A member of the tumor necrosis factor receptor (TNFR) superfamily, it is a 45 kD protein expressed on peripheral T cells, memory B cells, NK cells, and thymocyte subset. Through its ligand, CD70, CD27 plays a key role in T cell and B cell interactions. Additionally, ligation of CD27 on naïve T cells may be ...
Rat's 27
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TīmeklisThe N27 cell line, when injected into the striata of 6-hydroxydopamine-lesioned rats (an animal model of PD) caused a time-dependent improvement in neurological deficits. …
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